Which of the top-four seeds has the toughest road to Louisville?

McPeak: We have some blue-blood programs with lower seeds in some of the brackets, and it will make for some incredible drama. Texas having to go through a dangerous USC team, Creighton and Penn State to earn a bid will be challenging but not impossible. I will be keeping a close eye on that part of the bracket.

But in terms of a top-4 seed, Nebraska needs to beat Wisconsin which is a very good team and beat them for the third time this season. It is really hard to beat a good team three times in one season.

Penn State doesn't have it easy with Creighton and two-time defending NCAA champ Texas in its bracket.

Voepel: Louisville, both for the path the Cardinals could face and the pressure to make the final four at home. We saw that pressure get to Minnesota in 2018 when the final four was in Minneapolis. The Gophers, then the No. 2 overall seed when the tournament only seeded the top 16, were upset on their homecourt by No. 15 seed Oregon in the regional semifinals. Minnesota had tried all that season to avoid talk of the final four, but it weighed heavily on them in that loss.

Louisville split its ACC matches against Stanford this season, so that would be a challenging regional final for the Cardinals. But they also may have to get past No. 4 seed Purdue in the regional semifinals; the Boilermakers were 25-6 overall and fourth (16-4) in the Big Ten. Purdue is on the short list of best programs to never make a final four.

Lyle: The left side of the bracket is going to get heated (meaning the Pitt and Louisville quarters). Playing Stanford for a third time would be really interesting for Louisville. I'm also watching Florida and Purdue in this quarter. Florida's Kennedy Martin should scare everyone. She has had double-digit kills every match of her career. In the Pitt quarter -- a possible SMU/Kentucky rematch would be interesting. UK swept the Mustangs in September. I think both of those teams, along with TCU and Oregon would be interesting to watch against Pitt.